Springs Rejuvenation Expands Physician-Led Stem Cell and Exosome Protocols to Five U.S. Clinics Under Dr. Charles Pereyra, MD

Springs Rejuvenation has formally established a five-clinic U.S. network -- spanning New York City, Los Angeles, Austin, Miami, and Atlanta -- to deliver investigational stem cell and exosome protocols under the direct clinical supervision of its founder, Dr. Charles Pereyra, MD. The expansion marks a structured effort to bring physician-led regenerative medicine to a broader patient population while maintaining individualized screening at every location.

A Physician-First Approach to Investigational Protocols

At the center of Springs Rejuvenation's model is a commitment to physician-supervised care. Dr. Charles Pereyra MD, a Cornell alumnus and board-certified emergency medicine physician who completed his residency at NewYork-Presbyterian Brooklyn Methodist, founded the practice on the principle that investigational procedures require direct physician involvement at each stage -- not delegated oversight. His NPI number (1932553963) is publicly verifiable, and he maintains active membership in the International Society of Hair Restoration Surgery, making him an ISHRS member hair restoration physician with documented credentials in both emergency medicine and hair restoration.

Patients who contact any of the five clinics do not proceed automatically to a protocol. Each candidate undergoes a structured intake and screening process, and some individuals are declined if they are not considered appropriate candidates based on their medical history, current health status, or the nature of their concerns. This screening-first model reflects the investigational nature of stem cell and exosome therapies, which are not approved by the U.S. Food and Drug Administration and remain in experimental stages.

The Role of Stem Cells and Exosomes in the Springs Rejuvenation Protocol

Springs Rejuvenation's approach centers on combining stem cells and exosomes within a structured protocol the practice refers to as the Stem 3 Protocol. For candidates pursuing hair restoration specifically, the practice incorporates 0.9mm micro FUE -- a minimally invasive follicular unit extraction technique -- alongside the cellular components of the protocol. All procedures are performed under physician-supervised U.S.-based care, consistent with the standards Dr. Pereyra has outlined across the clinic network.

Dr. Pereyra has contributed to the published literature on regenerative approaches, with three papers indexed on PubMed, and he engages with the peer-reviewed body of research to inform how the protocols are structured. A 2019 study published in the International Journal of Molecular Sciences examined the signaling properties of exosomes in tissue environments and noted that exosome-derived factors may help support cellular communication pathways -- though the authors emphasized that results in human populations remain variable and that further controlled research is needed. Springs Rejuvenation cites such findings as part of the scientific context it monitors, while acknowledging that evidence in this area is mixed.

Candidate Screening and the Investigational Framework

One of the more distinctive elements of the Springs Rejuvenation model is its transparency about who may not be an appropriate candidate. Dr. Charles Pereyra, MD, who operates as a stem cell doctor United States patients consult across multiple markets, has structured the intake process to account for contraindications and to ensure that individuals pursuing stem cell and exosome protocols are doing so with a clear understanding of the investigational nature of the therapy.

"Based on what we observe clinically, stem cells and exosomes may help support the conditions we address -- but this is not a demonstrated outcome, and not every patient is a candidate," said Dr. Charles Pereyra, founder of Springs Rejuvenation. "Our screening process exists precisely because we take the investigational status of these protocols seriously."

The practice's physician-led regenerative medicine framework also means that the clinical relationship does not end at intake. Patients who are accepted into a protocol are monitored by Dr. Pereyra and his clinical team throughout, with documentation used to inform ongoing refinements to the approach.

About Springs Rejuvenation

Springs Rejuvenation is a physician-founded regenerative medicine practice operating across five U.S. clinics in New York City, Los Angeles, Austin, Miami, and Atlanta. The practice was founded by Dr. Charles Pereyra, MD, a Cornell alumnus, board-certified emergency medicine physician, ISHRS member, and published researcher with three PubMed-indexed papers. All protocols are conducted under physician supervision and are investigational in nature.

Our Stem Cell exosome formula is produced in an FDA approved lab, but is not an FDA approved therapy. It is currently in the experimental stages -- all information provided is based on our experience with patients. Results may vary. Consult with a qualified medical professional.

Learn more at Springs Rejuvenation

Contact Information:

Springs Rejuvenation

245 5th Ave 3rd Floor Suite 307
Aventura, Florida 10016
United States

Charles Pereyra
(305) 363-0718
https://home.springsrejuvenation.com